Mathieu Orfila was known as the father of toxicology. He published many books “Traite des poisons”, “Elements de chimie medicale”, “Lecons de medecine legale” and many more. Many of his publications were about his experimental observations on the symptoms of different kinds of poisonings, as well as the appearances which poisons leave in a dead body ("Classic Encyclopedia"). In 1840 forensic toxicology evidence was first used with the help of James Marsh, by the use of the Marsh test. This test was created by James Marsh in 1836 and was developed to detect the presence of arsenic in the human body. With this new method arsenic poisoning was found in Marie Lafarge husband’s body and she was convicted (Deslich 4).
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